When evaluating a patient with stable chest pain and no known coronary artery disease (CAD), how does the clinician decide whether to order imaging or other diagnostic tests? One approach involves a ...

Adding clinical risk factors and a coronary artery calcium (CAC) score to the conventional diagnostic algorithm for chest pain improves the prediction and discrimination of patients with suspected ...

Among patients with suspected obstructive CAD, two simple models that include clinical risk factors both outperform the commonly used pretest probability (PTP) model when it comes to predicting the ...

There is broad consensus that widespread SARS-CoV-2 testing is essential to safely reopening the United States. A big concern has been test availability, but test accuracy may prove a larger long-term ...

A blood-based biomarker test aided diagnosis and clinical management of Alzheimer’s disease by detecting brain amyloidosis in symptomatic patients, researchers reported at the Clinical Trials for ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...