“The patient’s history ... Gizmodo reached out to experts at Case Western University’s National Prion Disease Pathology ...

There is currently no cure for prion disease, and the new approach could be an important step towards treatments that prevent the disease or slow its progression in patients who have already ...

Prion disease affects the brain, leading to neurodegeneration and ... However, like gene editing, CHARM should be able to permanently silence a gene, meaning that patients should only need to take ...

There is currently no cure for prion disease, and the new approach could be an important step towards treatments that prevent the disease or slow its progression in patients who have already ...

Prion diseases such as CWD ... “Even if the risk was 0.005 percent,” Bradshaw says, “I don’t want to be patient zero.” ...

Context: Fatal familial insomnia (FFI) is a genetically transmitted neurodegenerative prion disease that incurs great ... paper describes the efforts of 1 patient (with the rapid-course Met ...

and Creutzfeldt–Jakob disease (CJD) in humans. In TSEs the normal cellular prion protein (PrP C) is transformed into an infectious disease-associated isoform, PrP Sc — a potential target for ...

this has been termed a 'subversion of function'. If so, PrP C contributes to neurotoxicity in prion disease but by uncertain mechnisms.

Feraud Director of the Center for Alzheimer’s Disease Research, wins the 2025 Rainwater Prize for Innovative Early-Career ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50% in a mouse model of the fatal neurodegenerative ...