“The patient’s history ... Gizmodo reached out to experts at Case Western University’s National Prion Disease Pathology ...

There is currently no cure for prion disease, and the new approach could be an important step towards treatments that prevent the disease or slow its progression in patients who have already ...

There is currently no cure for prion disease, and the new approach could be an important step towards treatments that prevent the disease or slow its progression in patients who have already ...

and Creutzfeldt–Jakob disease (CJD) in humans. In TSEs the normal cellular prion protein (PrP C) is transformed into an infectious disease-associated isoform, PrP Sc — a potential target for ...

this has been termed a 'subversion of function'. If so, PrP C contributes to neurotoxicity in prion disease but by uncertain mechnisms.

Orphan drugs offer critical treatment options for rare diseases, improving quality of life for underserved patients and ...

Viralgen and Axovia Therapeutics are partnering to develop and manufacture a gene therapy for the treatment of retinal ...

The product was withdrawn after some patients received prion-contaminated cadaveric growth hormone and subsequently died of Creutzfeldt-Jakob disease. In 2015, Collinge and co-authors reported ...

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50% in a mouse model of the fatal neurodegenerative ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...