Conditioned Pain Modulation (CPM) describes the endogenous process by which one painful stimulus reduces the perception of a second painful input. This “pain-inhibits-pain” phenomenon reflects the ...

Researchers at Karolinska Institutet in Sweden might have found an explanation for why people with self-injury behavior generally feel less pain than others. The key seems to be a more effective ...

Pain emerges from a complex interplay of peripheral transduction, spinal integration and supraspinal modulation. At the periphery, specialised nociceptors convert thermal, mechanical or chemical ...

Share on Pinterest A recent study used computational methods to identify novel compounds that activate receptors involved in pain modulation without sedation. Peter Dazeley/Getty Images Research on ...

This new article publication from Acta Pharmaceutica Sinica B, discusses allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Neuropathic pain is a ...

Among veterans with low back pain, a sequenced care pathway and a pain navigator pathway demonstrate similar physical function outcomes.

Researchers at Karolinska Institutet in Sweden might have found an explanation for why people with self-injury behaviour generally feel less pain than others. The key seems to be a more effective pain ...