The accumulation of misfolded or damaged proteins in long-lived, non-dividing cells like neurons are linked to neurodegenerative diseases like Alzheimer's. A study now finds that the build-up of these ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

Primordial germ cells, which emerge around day 16 in early human embryos, develop to form oogonia so that eventually, the number of oocytes that are present in an adult female is fixed at birth. After ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...

ELVAs pictured under a microscope. The ‘superorganelle’ roams the cytoplasm, capturing and holding onto toxic protein aggregates to protect oocytes from their toxic effects. Oocytes are immature egg ...