Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple ...

Liver cancer in children is rare, but when it occurs, the two main types are hepatoblastoma (HB) and hepatocellular carcinoma (HCC). In some cases, however, the tumors show features of both types.

New research published in Nature finds that tumor cells within supratentorial ependymomas (SE)—an aggressive childhood brain cancer—cluster into distinct tumor cell populations. Much like a ...

BPDCN is an aggressive type of blood cancer that originates from plasmacytoid dendritic cells (pDCs), a component of the immune system that produces type 1 interferon cytokines. These cytokines help ...

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program. Scientists at St ...

Immunotherapy has revolutionized cancer treatment, yet response rates remain highly variable across tumor types and individual patients. Increasing evidence ...

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor's cancerous cells influence their surroundings, blocking the body's immune defenses and creating a sort of haven ...

Cancer immunotherapies often rely on activating immune responses, yet many tumors remain resistant because their internal survival mechanisms are poorly understood.