Molecular motors are nanomachines that convert chemical energy to mechanical work for unidirectional movement. Actomyosin motors have been extensively studied over more than half a century, as ...

Conformational changes within myosin lead to its movement relative to an actin filament. Several crystal structures exist for myosin bound to various nucleotides, but none with bound actin. Therefore, ...

After five years of work, a team from National Biosciences Laboratory (LNBio), in the city of Campinas, has defined the three-dimensional structure of what is called the functional, or active, region ...

A visualization made from nearly 100,000 electron microscope images has revealed the ingenious way a protein involved in muscle activity shuts itself down to conserve energy. The protein is called ...

Researchers have characterised changes in the structure of motor proteins, called myosins, and energy consumption that occur during hibernation, highlighting key differences in large and small ...

Myosin in muscles behaves in a unique way, which might explain why muscles have such strong contractile power. A cartoon showing the asymmetry in the weak binding between myosin and actin that biases ...

Cells use the polymerization of actin alone to create some types of movement, but many other forms of movement require interplay between actin and an enzyme called ...

For the first time, scientists at University of Leeds reveal a complex mechanism behind blood clotting. The findings, published in Science Advances, visualise a key component of blood clotting - ...