In this issue of Nature Metabolism, Li et al. reveal that disruptions in mitochondrial protein folding are an early trigger of β-cell dysfunction in type 2 diabetes and highlight that LONP1 has a key ...

Researchers discovered that declining levels of phosphatidylcholine may be a major cause of age-related mitochondrial ...

Sepsis-associated acute kidney injury (SA-AKI) is a common complication in critically ill patients, characterized by high morbidity and mortality rates. It remains primarily treated with supportive ...

For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson's disease. But a critical question remained: do the failing mitochondria cause ...

Scientists know that colorectal cancer cells require large amounts of iron and that as cancer becomes more aggressive, the ...

Discover C15 reports mitochondrial health is crucial for energy, aging, and disease, emphasizing its role in fatigue, burnout ...

Patients with rare mitochondrial diseases already face a host of serious health issues, from muscle weakness to neurological problems and heart conditions. But one of their most life-threatening ...

When people think about health, they often focus on specific organs like the heart or brain. But many changes related to chronic conditions or ageing begin in the smallest units of your body — your ...

A new study published in Engineering has uncovered a regulatory mechanism linking lysosomal function to mitochondrial ...

The human heart is one of the hardest-working organs in the body. It never takes a day off and requires a continuous supply ...

Gladstone's Ken Nakamura (right) led a study that strengthens the links between energy breakdown in cells and the onset of Parkinson’s, potentially illuminating new paths for treatment. Here, Nakamura ...