What is the cellular microenvironment composed of? A cell’s microenvironment includes the extracellular matrix; similar or dissimilar cells that surround another cell; different cytokines, hormones, ...
Omics-driven insights into tumor microenvironment determinants of immunotherapy response in melanoma
Immunotherapy has revolutionized cancer treatment, yet response rates remain highly variable across tumor types and individual patients. Increasing evidence ...
Leone et al. 2 recently reported that JHU083, an antagonist of glutamine metabolism, suppresses cancer-cell growth and stimulates antitumor T-cell function. Cancer cells take up glutamine, glucose, ...
Constructing genetic-immune prognostic subtypes of primary duodenal adenocarcinoma through whole exome sequencing and AI-assisted immune microenvironment analysis. Median overall survival (months) in ...
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