In SetPoint you need to set the buttons to key presses that you don't use when you're playing. Like N, J, K, L, ;, etc. You can either do this for all applications, or figure out which .exe is running ...
Ergonomic mice are everywhere now, but the Logitech Lift is one of the more approachable ones, falling somewhere between casual gear and specialty equipment. Sitting at your desk for hours on end ...