People living in regions where malaria outbreaks are common experience repeated exposure to the disease, which gradually ...

The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained at early life, with implications for understanding and treating immunodeficiency, ...

An initiative partly funded by the Wellcome Trust Sanger Institute in the UK has moved further towards its goal of producing a 'human cell atlas' (HCA) to map every cell type in the human body.

In a recent review published in the European Journal of Immunology, a group of authors summarized current advances, challenges, and future directions in human systems immunology using multi-omics ...

The miniature models could exponentially accelerate vaccine development, cancer treatment research, and improved health outcomes across a spectrum of diseases. The left image shows the immune organ-on ...

The immune system acts as a critical sentinel of organismal aging, integrating the sensing of physiological states with the execution of defense and clearance functions. Immunosenescence not only ...

Medical researchers have used animals, particularly mice, to mimic disease and study biological phenomena. The origin of mice as a standard model system for scientific research can extend back to the ...

Human peadiatric thymus image from the IBEX protein multiplex (44 proteins on the same image) platform. Thymic epithelial cells are labeled with DEC205 (cyan), pan-cytokeratin (purple), keratin 5 (red ...