RNA therapeutics have emerged as one of the most promising new classes of medicines. Eight small interfering RNA (siRNA) ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

Oceans churned with lava. Air filled thick with smoke. Asteroids stormed down incessantly. Life during the Hadean Eon four billion years ago was a struggle, and yet that was when it began. 1,2 With no ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...

Using circular RNA, we’ve developed a platform we call isCAR™ for the in vivo delivery of CARs to immune cells. RNA is transient, but circular RNA, compared to linear mRNA, persists much longer in ...

Recent research showed that an artificially constructed self-replicating RNA system modeling primitive life at the origin of ...

Two human cells making RNA made visible by the bioluminescent lantern in pink (middle image). On the left, the same cells making a fluorescent protein that's distributed evenly throughout the two ...