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"The changes that happen with the fat exposure, the changes in metabolism and the changes in histone methylation and gene ...
The most popular of these treatments aim to alter either DNA methylation or histone acetylation. Inhibitors of DNA methylation can reactivate genes that have been silenced. Two examples of these ...
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News Medical on MSNExploring citrullination as a key regulator of gene expression and diseaseCitrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.
Using animal models, he, Dempsey, and the rest of their research team found that H3K36 methylation—a biochemical process that occurs within the H3 histone protein—is responsible for turning ...
This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...
To compact the DNA, plants use various epigenetic marks, including DNA methylation and modifications of the histone proteins ...
EZH2, a core component of the Polycomb Repressive Complex 2 (PRC2), plays a fundamental role in silencing tumor suppressor genes through histone methylation. Its overexpression has been implicated ...
Mutations fuel evolution while also causing diseases like cancer. Epigenome-targeted DNA repair can help organisms protect important genomic regions from mutation. However, the adaptive value, ...
Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact ...
Using animal models, he, Dempsey, and the rest of their research team found that H3K36 methylation -- a biochemical process that occurs within the H3 histone protein -- is responsible for turning ...
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