New mutations in TP53 gene drive resistance to p53-targeted cancer therapy

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...
News Medical

How Do Genetic Mutations Cause Disease?

Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

JPM26: Opus Genetics builds momentum in rare retinal gene therapy

Two of Opus's seven gene therapy assets are in clinical trials, with additional programs expected to enter the clinic.

Rare genetic form of diabetes detected in newborn babies for first time

A rare form of diabetes affecting newborn babies and caused by a genetic disorder has been discovered by scientists in the UK ...

Exploring mutations that spontaneously switch on a key brain cell receptor

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...
Futurism

Scientists Create Ultimate Antiviral Using Rare “Superpower” Genetic Mutation

A rare genetic mutation that causes a deficiency in an immune regulator called ISG15 is known to make people more vulnerable to some bacterial infections and cause persistent inflammation — but it can ...
Rolling Out

The rare genetic mutation that prevents wrinkles

Meet the luckiest people on Earth — individuals carrying a rare genetic mutation that prevents wrinkles from forming even as they age well into their 80s. These genetic lottery winners have provided ...

Childhood deafness: Researchers identify over 200 mutations, including previously unknown variants

Deafness, the most common sensorineural hearing loss at all stages of life, occurs either independently or as part of ...