We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. SCOTTSDALE, Ariz. — A novel therapeutic approach ...

Kristi Baker, Shuo-Wang Qiao, Timothy T. Kuo, Victoria G. Aveson, Barbara Platzer, Jan-Terje Andersen, Inger Sandlie, Zhangguo Chen, Colin de Haar, Wayne I. Lencer, Edda Fiebiger, Richard S. Blumberg ...

The neonatal Fc receptor (FcRn) plays a crucial role in maintaining IgG homeostasis by binding to immunoglobulins in a pH-dependent manner. This receptor not only recycles IgG, thereby extending its ...

The ongoing coronavirus disease 2019 (COVID-19) pandemic has caused an economic and healthcare crisis. COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a ...

In therapeutic antibody development the fragment crystallizable (Fc) region is far more than just an antigen-binding aid; it's role is much larger, functioning as the antibody’s functional control ...

Two new antibodies may treat autoimmune diseases by reducing inflammation through blocking the immune receptor FcγRI.

Takenobu Y, Kikuchi T, Ishikawa D, et al. Rozanolixizumab as rescue therapy in triple seronegative refractory generalized ...

An international research group directed by UMC Utrecht has developed and characterized two first-in-class antibodies that ...

Your eyes—retinal blood vessels and retinal imaging—may help predict heart disease, according to a new study. Here, doctors ...

Scientists have used their discovery of previously unknown mechanisms in an anti-inflammatory pathway to develop a powerful upgrade: an engineered antibody that delivers the effectiveness of IVIG at ...

On November 5, 2025, argenx SE announced that Health Canada approved VYVGART SC (efgartigimod alfa injection) as a monotherapy for adults with active chronic inflammatory demyelinating polyneuropathy ...