The ensemble-function approach provides a quantitative catalytic model for serine proteases and identifies repeatedly evolved catalytic strategies. Credit: Science (2025). DOI: 10.1126/science.ado5068 ...

Chemists created an enzyme with boronic acid at its reactive center. This approach can produce more selective reactions with boron, and allows the use of directed evolution to improve its catalytic ...

Photodynamic therapy (PDT), characterized by its non-invasive nature and precise spatiotemporal selectivity, has garnered considerable attention for its applications in tumor and anti-infection ...

Researchers have developed a new workflow for designing enzymes from scratch, paving the way toward more efficient, powerful and environmentally benign chemistry. The new method allows designers to ...

Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life – how enzymes are ...