Hormone systems, which control diverse physiological functions, have been extensively studied, yet consistent rules underlying these systems remain elusive. Here we identify unifying design principles ...

Organoids—tiny, lab-grown 3D clusters of cells—are a useful tool for studying organ development, disease, and drug responses. These miniature organs-in-a-dish are powerful, but they’re not perfect: ...

Professor Deng Hongkui's team from the Peking University School of Life Sciences has made the first successful differentiation of human pluripotent stem cells into fully endocrine-subtype-complete ...

Remarkable advances in protocol development have been achieved to manufacture insulin-secreting islets from human pluripotent stem cells (hPSCs). Distinct from current approaches, we devised a tunable ...

Toward the goal of elucidating endocrine system aging mechanisms, this study establishes the first single-cell aging atlas across multiple endocrine organs. The research reveals conserved aging ...

Immunofluorescence image of the pancreatic islets of a 50-year-old-female without diabetes. This individual had 54% beta cells (GREEN), 9% delta cells (WHITE) and 37% alpha cells (RED). Diabetes is ...

Endocrine therapy is a way of treating conditions such as cancer using hormones. Also known as hormone therapy, it involves adjusting the levels of certain hormones, such as testosterone, estrogen, ...