Grey's Anatomy has never been shy about killing off a main character for story purposes or to fulfill an actor's wish to leave the series. However, the death that still resonates in everyone's mind is ...

When Grey's Anatomy took off as a cultural phenomenon in the mid-2000s, Patrick Dempsey's Dr. Derek Shepherd also swiftly became one of the biggest heartthrobs on television. Nicknamed "McDreamy" by ...