A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial "checkpoint" that enables dendritic cells to efficiently activate T ...

Dendritic cells occupy a pivotal role at the nexus of metabolism and immune regulation, employing distinct bioenergetic programmes to calibrate antigen uptake, processing and presentation. In their ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" ...

Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...

(MEMPHIS, Tenn. – April 02, 2026) St. Jude Children’s Research Hospital scientists have discovered how tumors disable immune “gatekeeper” cells that alert the rest of the immune system to the presence ...

The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or "tolerate" molecules found on ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

Immunotherapy uses a person's own immune system to fight cancer. Immune checkpoint inhibitors are one class of immunotherapy that block specific proteins from slowing the immune response. As a result, ...

Chronic diabetic ulcers represent one of the most challenging complications in modern healthcare, affecting over 131 million people worldwide and generating approximately $755 billion in annual ...

Central epithelial nerve fiber density and related architectural metrics remain profoundly reduced up to two years post-LASIK, with parallel increases in mechanical (but not osmotic) sensory ...