When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications, an ...

In a twist on the question, 'Which came first, the chicken or the egg?', scientists have long faced a similar question about how human adenovirus replicates: 'Which comes first, assembly of the viral ...

If the engines of DNA replication stay in high gear all the time, they eventually stall or even break down. Fortunately, these engines, which consist of protein complexes, have what could be called ...

Every person starts as just one fertilized egg. By adulthood, that single cell has turned into roughly 37 trillion cells, many of which keep dividing to create the same amount of fresh human cells ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...