The biguanide metformin (dimethylbiguanide) was initially introduced for the treatment of type 2 diabetes mellitus in the late 1950s. Today, this drug is considered to be the first-choice agent and ...

Warfarin is one of the most widely used drugs in the world for a variety of indications involving the prevention and treatment of thromboembolic phenomena. Even after 60 years of its use, warfarin's ...

Osteoarthritis affects 600 million people worldwide, making it a leading cause of disability. With no disease-modifying treatments available or on the horizon, oral non-steroidal anti-inflammatory ...

Appropriate drug prescribing is an ongoing challenge and may at times generate controversy. Whether we have adequate and reliable data to alter our prescribing of the antihyperglycemic agent metformin ...

Please provide your email address to receive an email when new articles are posted on . One of the most difficult things we ever have to tell a patient is: “You are not a good candidate for LASIK.” ...

These specific contraindications cause consternation for clinicians who may wish to prescribe metformin but do not want to put their patients at risk of lactic acidosis or expose themselves to ...

The absolute contraindications for laparoscopic cholecystectomy from the 1980s (pregnancy, previous abdominal surgery, bowel obstruction, coagulopathy, obesity, cirrhosis, inability to tolerate ...

A new study has found that people with newly diagnosed OA (knee or hip) with contraindications to or precautions for NSAIDs use continue to be prescribed these drugs. Additionally they had higher use ...