DNA inside human cells is not just floating around freely. It is tightly wrapped around small proteins, forming a long chain.
Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...
There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will fit into a cell’s nucleus, while the crucial parts of it remain accessible ...
Researchers have discovered that the motion of chromatin, the material that DNA is made of, can help facilitate effective repair of DNA damage in the human nucleus -- a finding that could lead to ...
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The first 3D mapping of the human genome

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...
In a recent study published in Nature Medicine, researchers map the diverse cell types present in healthy breast tissue to elucidate the role of genetic ancestry in breast cancer risk. Study: ...
Researchers in Japan have discovered that the local DNA motion inside of human cells remains steady throughout interphase, where the cell grows and replicates its DNA for cell division. The study ...
Nucleosomes (blue sphares) in active chromatin regions form condensed domains with local nucleosome contacts and cohesin (rings), where nucleosomes fluctuate. Each interphase chromosome (highlighted ...
One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
DNA might be too small to see with the unaided eye, but it packs our cells in shocking quantities: More than six and a half feet of DNA lies within every cellular nucleus. It squeezes into such a ...