The common conception of DNA is in long, twisting strands, but in order to fit into the confines of the nucleus, DNA actually condenses into a strict structure called chromatin. Chromatin facilitates ...

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

Inside the nucleus of a cell, the chromatin fiber interacts with itself to condense into a chromosome. The chromatin fiber also supports gene expression and replication of chromosomal DNA.

To overcome the problem of visualizing chromatin in an intact nucleus, O'Shea's team screened a number of candidate dyes, eventually finding one that could be precisely manipulated with light to ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

Harvard University researchers at the Broad Institute report that expansion in situ genome sequencing (ExIGS) linked nuclear abnormalities to hotspots of aberrant chromatin regulation, potentially ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

Inside a nucleus, chromosomes jumble together like a game of Twister. This can bring regulatory elements, such as enhancers, from one chromosome into contact with genes from another chromosome, ...

A multidisciplinary team of Indiana University researchers have discovered that the motion of chromatin, the material that DNA is made of, can help facilitate effective repair of DNA damage in the ...

But archaea do not have a nucleus, and their small circular genomes are easier to package inside their cells. “If the primary role for chromatin is not packaging, it might instead be to regulate gene ...