Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, ...

A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

However, the structure of chromatin also appears to serve a second, possibly more important role, in that it gives eukaryotic cells the capability to exert complex levels of control over gene ...

Scientists at St. Jude Children’s Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to ...

During interphase, individual chromosomes are not visible, and the chromatin appears ... Because the centrosomes are located outside the nucleus in animal cells, the microtubules of the developing ...

Varshavsky studied chromatin structure and wanted to develop new methods to detect the DNA-protein interplay in intact cells. Motivated to better understand chromatin structural organization, ...

How chromatin openness controls behavioral changes remains unclear. This work implicates alternative promoter selection, ...

New research delves into the DNA details and chromatin structures that may predict prognosis in early-stage lung ...

A novel technique to visualize gene-active and gene-repressive DNA regions in living cells, developed by a ...

The work was published today in Cell Research. Chromatin comprises sections of DNA wrapped around proteins called histones to form nucleosomes collectively. One chromatin remodeling mechanism ...