Taking images of tiny structures within cells is tricky business. One technique, cryogenic electron tomography (cryoET), ...

Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

Fast, gentle, and highly specific glycoprotein labeling compatible with downstream immunofluorescence, enabled by ...

Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

Optical diffraction tomography (ODT) has long been recognized for its potential in non-invasive, label-free imaging of live biological cells. However, a major challenge arises when ODT is applied to ...

Workflow of the optimized deep imaging protocol for optically cleared skeletal tissue. Steps for preparing the deep-imaging bone hemisections, including tissue fixation, decalcification, dehydration, ...

Cell painting has established itself as a powerful tool for high content imaging, able to generate vast quantities of data in response to chemical perturbations. Over the past decade, cell painting ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...

While medical centers use ultrasound daily, so far this technology is not capable of observing body tissues at the scale of cells. Physicists from TU Delft have developed a microscopy technique based ...