Researchers have mapped variation in human stem cells that explains how cells of an individual may shape a unique 'developmental dance' at the molecular level, thereby controlling how the brain and ...

The development of humans and other animals unfolds gradually over time, with cells taking on specific roles and functions via a process called cell fate determination. The fate of individual cells, ...

Successfully producing large quantities of biotherapeutics, including monoclonal antibodies and recombinant protein products, depends on robust and reliable cell line development (CLD). Issues that ...

A new cellular atlas charts, in unprecedented detail, how human B cells are built step by step — and offers a window into how this developmental process goes awry in leukemia. The KAUST-led ...

A 'pocket' on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Cell division is key for life. Every organism -- from the smallest yeast ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

Single-cell analysis is reshaping drug discovery, but interpretation remains slow. AI single cell approaches may close the ...