Inhibitors of apoptosis, ferroptosis and other cell death mechanisms had no effect on this process, suggesting disulfidptosis is a distinct pathway. The discovery of disulfidptosis offers a new ...

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a ...

Cell Death Discovery is a multidisciplinary, international, online-only, open access journal, dedicated to publishing research at the intersection of medicine with biochemistry, pharmacology ...

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause ...

Glaucoma is a progressive eye disorder characterized by fluid buildup inside the eye, causing ocular hypertension. By 2040, ...

Scientists uncover how a genetic mutation linked to Huntington's disease stays harmless for years before expanding and causing cell death. The study discovers that DNA repeats must exceed 150 CAGs to ...

The discovery of a new type of stem cell in the brain could usher in better treatments for the deadliest brain tumor. UCSF scientists have discovered a stem cell in the young brain that's capable of ...

Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model ...

Macronucleophagy helps control micronucleophagy to protect yeast cells during stress. Through extensive experiments with ...

Unlike other forms of cell death, necroptosis shares features of ... “AI provides reliable tools and methods for drug discovery, such as virtual screening, quantitative structure-activity ...

During islet development, beta-cell death, rather than proliferation alone, regulates beta-cell mass and shapes the immune ...