CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice. Arthritis Rheum. 60 , 123–132 (2009). Article CAS Google Scholar ...
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Microbes in your gut could determine cancer treatment outcomesResearchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment ...
ONC-392 targets CTLA-4 in a way that selectively eliminates tumor-infiltrating regulatory T cells without affecting peripheral T cell activation by a mechanism illustrated in Fig. 1. Compared with ...
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