New users of LAMA-LABA therapy had a 20% reduction in the rate of first pneumonia hospitalization compared with new users of ICS-LABA (HR, 0.80; 95% CI, 0.75-0.86).

Treatment with long-acting muscarinic antagonists (LAMA) plus long-acting β-agonists (LABA) is associated with fewer exacerbation events in patients with chronic obstructive pulmonary disease (COPD) ...

The new long-acting muscarinic antagonist and long-acting beta-agonist (LAMA/LABA) fixed dose combination (FDC) inhaler may be a better option than inhaled corticosteroids (ICS) for long-term use.

The researchers found that in patients with COPD, new LABA and LAMA use was associated with a 1.5- and 1.52-fold increased cardiovascular risk within 30 days of initiation, respectively; with ...

Lung function was significantly improved with LAMA/LABA therapy compared with patients receiving preoperative LAMA therapy (FEV1, 223.1 mL vs. 130 mL; FEV 1 percent predicted, 10.8% vs. 6.8%).

In any case, "Feldman and colleagues' study provides assurance to patients and clinicians when choosing a dry-powder inhaler over a metered-dose inhaler of LABA-LAMA-inhaled corticosteroid in a ...

Based on GOLD criteria, LAMA, LABA or LAMA+LABA therapy should be used as the initial treatment for the majority of patients with COPD, regardless of exacerbation risk. With the 2023 Report, GOLD no ...

Chronic obstructive pulmonary disease (COPD) treatments involving inhaled corticosteroids ... LAMA/LABA, or placebo groups). Follow-up periods of the studies ranged from 3 to 36 months. ...

Many medications can help relieve your COPD symptoms. ... LABA/LAMA as first-line therapy for COPD: A summary of the evidence and guideline recommendations. https: ...

In a cohort study, Feldman and colleagues analyzed 137,833 adults (mean age, 70.2 years; 50.4% women) from Optum’s Clinformatics Data Mart with COPD who were newly prescribed either LAMA-LABA ...

The other single-inhaler on the market for COPD triple therapy, fluticasone-umeclidinium-vilanterol, is a dry-powder inhaler that does not contain hydrofluoroalkane-134a.