Cytogenetic studies of bone marrow should ... Current Status of Treatment for Chronic Myelogenous Leukemia. MedGenMed 2(2), 2000 [formerly published in Medscape Hematology-Oncology eJournal ...

As the field of human cytogenetics emerged ... translocation event involving chromosomes 9 and 22 was responsible for CML (Rowley, 1973). G-banding methods continue to be widely used today ...

Table 1. Cytogenetic and molecular response rates of large clinical trials testing first-line high-dose imatinib in chronic-phase chronic myeloid leukemia. Study (year) Trial Response (%) Ref.

In the case of CML, a disease in which patients have too ... As Nowell (2007) recounts: I knew nothing about cytogenetics at this time but felt that the chromosomal preparations of the leukemic ...

Chronic Myeloid Leukemia (CML) CML ... and KMT2A rearrangements. The use of cytogenetics, FISH, and NGS panels aids in classification, prognostication, and treatment selection.