2025 NFL Week 16 odds, betting
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Eleven games have spreads of four points or fewer, and nine home teams are catching points as underdogs. Mix in late-season motivations, banged-up rosters, along with winter weather, and escaping Week 16 could be the most impressive feat for poolies this year.
The best team in the NFL right now is the Los Angeles Rams, and the second-best team is the Seattle Seahawks. That much remains the same from our betting power ratings last week, though the gap between the two has widened after the Seattle offense and Sam Darnold had their third rough outing in a five-game stretch.
See the top projected fantasy running backs for Week 16. Our rankings highlight the best RB options to start in your fantasy football lineup.