The new technique is called CLASSIC, an acronym for “combining long and short range sequencing to investigate genetic ...

Commonly used sequencing approaches do not capture full information from both genetics and epigenetics. Some of these may involve separate, parallel workflows and sequencing to produce full ...

DNA is the poster child for high-specificity binding. As long as their base sequences match, two complementary strands of DNA can navigate through a sea of biomolecules, find each other, and hold fast ...

Scientists have long known that human genes spring into action through instructions delivered by the precise order of our DNA, directed by the four different types of individual links, or "bases," ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

It’s a story UC Santa Cruz Research Professor David Deamer has told many times before: in 1989, while driving along a forested road in Oregon on his way to visit family, an idea struck him. Like many ...

At least five groups have independently invented a new class of CRISPR gene editing tools called dual base editors. The systems combine the functions and components of two CRISPR base editors, which ...