Atrioventricular septal defect is a developmental irregularity in which a hole connects two or more chambers in your child’s heart. This hole may connect the top two, the bottom two, or all four ...

The genetic etiology of atrioventricular septal defect (AVSD) is unknown in 40% cases. Conventional sequencing and arrays have identified the etiology in only a minority of nonsyndromic individuals ...

Since 1990, the mortality rate for children born with Down syndrome and a congenital heart defect has more than halved. This has been shown by a study by the University of Gothenburg. However, the ...

The goal of this study was to identify the contribution of large copy-number variants to Down syndrome–associated atrioventricular septal defects, the risk for which in the trisomic population is ...

An atrioventricular canal is a congenital heart defect that connects chambers of your child’s heart that shouldn’t be connected. Atrioventricular canals usually require surgical treatment. It usually ...

An atrioventricular septal defect (AVSD) is a condition in which there is a hole between the chambers of the left and right sides of the heart. Additionally, the valves between the chambers may not ...