The core finding: newborns who developed severe E. coli sepsis had significantly lower levels of maternally transferred anti-E. coli antibodies than matched infants who remained well. In other words, ...

Monoclonal antibodies are among the most widely used biologic medicines, with applications ranging from cancer treatment to autoimmune disease therapy. However, during manufacturing, storage, or ...

Therapeutic antibodies are among the most widely used biologic medicines, yet detecting subtle structural differences in these complex proteins remains challenging. Researchers in Japan have ...

A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.

A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.

Doctors of Meenakshi Mission Hospital has successfully used monoclonal antibody therapy to treat Anti-Glomerular Basement Membrane disease, helping a patient recover kidney function and come off ...

In the aftermath of those cases, some practitioners have suggested means-plus-function claiming as one strategy to obtain antibody claims that are broader in scope than the specific antibodies ...

In a recent study posted to the bioRxiv* preprint server, researchers explored the differences in infant and maternal cord antibody functions between severe acute respiratory syndrome coronavirus 2 ...

b) an Fc domain comprising amino acid substitutions M428L/N434S as compared to a human Fc polypeptide, wherein numbering is according to the EU index of Kabat, wherein said anti-C5 antibody with said ...