The carving up of the amyloid precursor protein (APP) by the successive action of β- and γ-secretases liberates Aβ, but also yields a small intracellular fragment, the APP intracellular domain (AICD).
Discover the latest articles and news in related subjects. RAW 264.7 cells were maintained in RPMI1640 medium supplemented with 10%FBS. For the induction of cell death, 5×10 5 cells/well were seeded ...
If you haven’t had to perform CPR for a patient who was being shocked by an automated implant­able cardioverter defibrillator (AICD), give it time. Approximately 800,000 people in the United States ...
When the amyloid precursor protein (APP) gets chopped up to make Aβ, other fragments are released, including APP’s intracellular domain. Scientists believe AICD acts as a transcription factor, though ...