Feasibility and potential benefit of neoadjuvant chemotherapy for colorectal liver metastasis: A single-centered retrospective study. Background: Concurrent chemoradiation with 5-fluorouracil (5-FU) ...
A single-blind, placebo-controlled, sequential design study evaluating the potential effects of trabectedin on the QT intervals. Background: 5-fluorouracil (5FU) plays an important role in induction ...
Fluorouracil (5FU) is a fundamental component of all chemotherapic combinations for palliative (Board and Valle, 2007) and adjuvant treatments (Chung and Saltz, 2007) of colorectal cancer. Its main ...
Dose-limiting toxicity affects 31–34% of patients treated with 5-fluorouracil (5-FU). Dihydropyrimidine dehydrogenase (DPD) is a key enzyme in the detoxification of 5-FU; patients with a complete or ...
When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient’s body surface area. This is estimated by plugging the patient’s height and weight into an equation ...
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